Now accepting Telehealth appointments. Schedule a virtual visit.

Bringing Evidence Based Neurosurgery to North Atlanta

Dr Mairaj Sami MD, a neurosurgeon at Apex Spine and Neurosurgery is a contributing author to the latest guidelines for the surgical treatment of glioblastoma, the most common primary brain tumor affecting adults.  Dr. Sami is bringing evidence-based neurosurgery to the citizens of Atlanta, GA.  If you, or anyone that you know, has been diagnosed with a brain tumor let Dr. Sami and the other providers at Apex Spine and Neurosurgery help guide you through your care.  See the abstract below:

 

Epub 2020 Nov 19.

Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update

Joseph S Domino, D Ryan Ormond, Isabelle M Germano, Mairaj Sami, Timothy C Ryken, Jeffrey J Olson

Abstract

Target population: These recommendations apply to adults with newly diagnosed or suspected glioblastoma.

Question: What is the effect of extent of surgical resection on patient outcome in the initial management of adult patients with suspected newly diagnosed glioblastoma?

Recommendation: Level II: Maximal cytoreductive surgery is recommended in adult patients with suspected newly diagnosed supratentorial glioblastoma with gross total resection defined as removal of contrast enhancing tumor. Level III: Biopsy, subtotal resection, or gross total resection is suggested depending on medical comorbidities, functional status, and location of tumor if maximal resection may cause significant neurologic deficit.

Question: What is the role of cytoreductive surgery in adults with newly diagnosed bi-frontal "butterfly" glioblastoma?

Recommendation: Level III: Resection of newly diagnosed bi-frontal "butterfly" glioblastoma is suggested to improve overall survival over biopsy alone.

Question: What is the goal of cytoreductive surgery in elderly adult patients with newly diagnosed glioblastoma?

Recommendation: Level III: Elderly patients (> 65 years) show survival benefit with gross total resection and it is suggested they undergo cytoreductive surgery.

Question: What is the role of advanced intraoperative guidance techniques in cytoreductive surgery in adults with newly diagnosed glioblastoma?

Recommendation: Level III: The use of intraoperative guidance adjuncts such as intraoperative MRI (iMRI) or 5-aminolevulinic acid (5-ALA) are suggested to maximize extent of resection in newly diagnosed glioblastoma. There is insufficient evidence to make a suggestion on the use of fluorescein, indocyanine green, or intraoperative ultrasound.

Keywords: Cytoreduction; Glioblastoma; Guideline; Surgery.

 

 

 

You Might Also Enjoy...

Understanding Pinched Nerve Conditions

Pinched nerves are caused by inflammation and compression of one or more of the body’s nerves. When surrounding tissues press on a nerve, you’ll feel pain, and possibly tingling or numbness, too.

Learn the Early Warning Signs of a Brain Tumor

A brain tumor doesn’t have to be cancerous to cause problems. If you know the early warning signs of a brain tumor, you can get prompt treatment. And the earlier you treat a tumor, the better your chances of success.

McKenzie Exercises for Back Pain

Many people experience some form of back pain in their lifetime. In the United States, back pain affects 75 to 85 percent of all adults.

5 Neck Exercises for Arthritis

We put a lot of impact on our joints over the years. Eventually they start to show the signs of wear and tear. With age, arthritis can cause the joints in our knees, hands, wrists, and feet to become stiff and sore.