APEX Spine and Neurosurgery has two new locations coming soon!

Bringing Evidence Based Neurosurgery to North Atlanta

Dr Mairaj Sami MD, a neurosurgeon at Apex Spine and Neurosurgery is a contributing author to the latest guidelines for the surgical treatment of glioblastoma, the most common primary brain tumor affecting adults.  Dr. Sami is bringing evidence-based neurosurgery to the citizens of Atlanta, GA.  If you, or anyone that you know, has been diagnosed with a brain tumor let Dr. Sami and the other providers at Apex Spine and Neurosurgery help guide you through your care.  See the abstract below:


Epub 2020 Nov 19.

Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update

Joseph S Domino, D Ryan Ormond, Isabelle M Germano, Mairaj Sami, Timothy C Ryken, Jeffrey J Olson


Target population: These recommendations apply to adults with newly diagnosed or suspected glioblastoma.

Question: What is the effect of extent of surgical resection on patient outcome in the initial management of adult patients with suspected newly diagnosed glioblastoma?

Recommendation: Level II: Maximal cytoreductive surgery is recommended in adult patients with suspected newly diagnosed supratentorial glioblastoma with gross total resection defined as removal of contrast enhancing tumor. Level III: Biopsy, subtotal resection, or gross total resection is suggested depending on medical comorbidities, functional status, and location of tumor if maximal resection may cause significant neurologic deficit.

Question: What is the role of cytoreductive surgery in adults with newly diagnosed bi-frontal "butterfly" glioblastoma?

Recommendation: Level III: Resection of newly diagnosed bi-frontal "butterfly" glioblastoma is suggested to improve overall survival over biopsy alone.

Question: What is the goal of cytoreductive surgery in elderly adult patients with newly diagnosed glioblastoma?

Recommendation: Level III: Elderly patients (> 65 years) show survival benefit with gross total resection and it is suggested they undergo cytoreductive surgery.

Question: What is the role of advanced intraoperative guidance techniques in cytoreductive surgery in adults with newly diagnosed glioblastoma?

Recommendation: Level III: The use of intraoperative guidance adjuncts such as intraoperative MRI (iMRI) or 5-aminolevulinic acid (5-ALA) are suggested to maximize extent of resection in newly diagnosed glioblastoma. There is insufficient evidence to make a suggestion on the use of fluorescein, indocyanine green, or intraoperative ultrasound.

Keywords: Cytoreduction; Glioblastoma; Guideline; Surgery.




You Might Also Enjoy...

Common Lifestyle Causes of Neck Pain

Neck pain is more than just a pain in the neck; it can affect the structure of your spine and the function of the nerves that run through it. Our team shares some common lifestyle causes of neck pain.

Treatment for Your Tarlov Cysts

Tarlov cysts are a bit of an enigma. They’re either too small to cause symptoms or so rare in their large, symptomatic form that many doctors misdiagnose them. Here’s why you need spine specialists like ours to diagnose and treat your Tarlov cysts.

Correcting Your Scoliosis

Scoliosis, a side-to-side curvature of the spine, disproportionately affects young girls, and often has no known cause. But there are treatments that can correct the problem. Learn more about this condition and what we can do about it.